Inhibition of IgG Multimer & Hexamer Formation Using an Fc Silent Extended Half-life Fc Fusion Protein
Time: 12:00 pm
day: Conference Day Two
Details:
• Design and structure of Fc silent artificial rheumatoid factor
• Review of IgG hexamer formation after immune complex formation
• Review of FcRn structure and function and how that can be used to extend the half-life of Fc proteins and monoclonal antibodies. Very brief discussion on FcRn being a cofactor of CD32a
