Antoinette Russell
Seminars
Thursday 31st July 2025
Alteration of Binding Affinity to FcGRs to Modulate Effector Function
9:30 am
• Analysis of library of known mutants to either increase or decrease effector functions
• Translatability of SPR binding to cellular assay activity (ADCC, ADCP, CDC)
• Influence of mutations in library on binding to FcRn
