Erik Procko

Erik Procko

Company: Cyrus Biotechnology

Job title: Director, Discovery


10:00 am Severing Fc Effector Functions from Antigen Binding; IgG Proteases for Autoimmunity 10:00 am

Discussing bacterial IgG protease IdeS cleaving antibodies in the hinge to decouple effector functions from antigen binding AI-guided removal of T cell epitopes and shielding of surface epitopes by glycoengineering to reduce Immunogenicity of IdeS  Extending pharmacodynamics by hyperglycosylation, creating a long-lived deimmunized IgG protease for deactivation and depletion of IgG autoantibodiesRead more

day: Conference Day Two

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