Joel Heisler

Company: Genentech

Job title: Postdoctoral Fellow, Antibody Engineering

Seminars:

Engineering Antibody Fc to Reduce Viscosity for Subcutaneous Delivery 12:00 pm

• Subcutaneous delivery of high-concentration antibody drug therapeutics is becoming increasingly prevalent due to several significant advantages including improved patient convenience, comfort, compliance, and healthcare cost • Antibody self-associations through Fab-Fc interactions are likely contributing to viscosity significantly more than the literature, which is dominated by evidence of Fab-Fab interactions would suggest • We show…Read more

day: Conference Day One