Alteration of Binding Affinity to FcGRs to Modulate Effector Function
Time: 9:30 am
day: Conference Day Two
Details:
• Analysis of library of known mutants to either increase or decrease effector functions
• Translatability of SPR binding to cellular assay activity (ADCC, ADCP, CDC)
• Influence of mutations in library on binding to FcRn
