FcRn-Guided Engineering of Antibody- & Albumin-Based Formats

Time: 3:00 pm
day: Conference Day Two

Details:

• FcRn is a homeostatic cellular regulator of both IgG and albumin
• The importance of considering cross-species FcRn-ligand binding differences when evaluating receptor-targeting molecules in mouse models
• Design of new antibody- and albumin-based formats with tailored pharmacokinetics and effector functions
• Engineering of antibody and albumin designs with enhanced or restricted transplacental transport properties