Roundtable Discussion: Optimising Fc-Engineered Antibody Stability & Developability to Improve Manufacturability & Shelf-Life for Reduced Development Costs & Improved Product Quality
Time: 10:00 am
day: Conference Day Two
Details:
• Implementing computational tools and predictive algorithms to identify potential stability and developability issues in the design process to reduce the risk of costly downstream failures and improve the efficiency of antibody development
• Utilising biophysical characterization techniques, such as differential scanning calorimetry (DSC) and dynamic light scattering (DLS), to accurately assess antibody stability and aggregation propensity to optimize manufacturability and shelf-life
• Develop optimized formulation strategies and manufacturing processes, and improve antibody stability and minimise degradation during production and storage to ensure consistent product quality and reduced development cost
